List of proposed courses and lectures:

Training modules for students

Polymeric NanoBioMaterials for medical applications. Training for academia, industry, research, suppliers

Implementation of Safe-by-Design approach for polymeric nanobiomaterials used for drug delivery. Case study: Chitosan

Computational Methods to Predict the Biological Effects of Additives used in Medical Applications

Nanomaterials Based-Products Awareness

Nanomaterials and Nanostructures: Synthesis and Characterization

Colloidal Phenomena in Natural Systems

Ecological Chemistry

 

Training modules for students
No. Title Speaker Participants Date
1 Safe-by-design concept applied to nanomaterials based devices used for drug Prof. Dr. Vasile OSTAFE Students from Medicinal Chemistry, Chemistry, Biology, Biochemistry 28.03.2019

10-12

2 Predictions on the effects of nanoparticle degradation products Prof. Dr. Adriana ISVORAN Students from Medicinal Chemistry, Chemistry, Biology, Biochemistry 28.03.2019

14-16

3 Applications of nanoparticles in medicine ( Lector Dr. Dana DASCĂLU Students from Medicinal Chemistry, Chemistry, Biology, Biochemistry 29.03.2019

10-12

4 Methods that can be applied to investigate the effects of nanoparticles on microorganisms drd. MATICA Adina Students from Medicinal Chemistry, Chemistry, Biology, Biochemistry 29.03.2019

14-16

5 Methods that can be applied to investigate the effects of nanoparticles on lower organisms drd. BOROS Bianca Vanesa Students from Medicinal Chemistry, Chemistry, Biology, Biochemistry 29.03.2019

16-20

 

 

 

Polymeric NanoBioMaterials for medical applications. Training for academia, industry, research, suppliers
Location: Advanced Environmental Research Laboratories, Timisoara (Romania)
Duration: 21 March 2019 (12:00 – 20:00)
Main speakers: Prof. Dr. Vasile OSTAFE, Prof. Dr. Adriana ISVORAN
Overview: Polymeric nanobiomaterials have obtained considerable attention for use in various biomedical applications. Biomaterials have been widely used in medical and pharmaceutical fields such as contact lenses, bone and dental implants, drug delivery, tissue regeneration, and the list can long continue. Nanotechnologies provide an essential task in the growth of biomaterial-based pharmaceutical and medical devices.

Many new nanomaterials are presently being tested for various complex and precise therapeutic diagnostics. Nanomaterials have become very appealing for drug delivery objectives due to their exceptional capacities and their minor side effects in cancer therapy and in the healing of other diseases. Whereas some nanomaterials are quickly progressing in their medical applications such as chitosan and liposomes, a few others are, at least for the moment, slowly advanced. Various methods in nanofabrication and nanomaterials synthesis are continuing to grow with the aim of developing new proficient, less costly, and more reproducible large-scale manufacture procedures.

Objectives: To provide applicants with an understanding about various medical uses of nanomaterials and to draw attention to their potential harmful effects. As in cases of other new medical devices and application, it is necessary to fully understand the potential toxic effects it may have. Especially in the case of nanomaterials, since their size and bio-accessibility lead to the potential for quick incorporation into organisms, the toxicological issues have to be fully considered and understood before the usage of the new devices based on nanomaterials on large scale on humans. A clear balance between the possible advantageous aspects of nanomaterials versus their potential harmful effects to humans should be realized. In this quest, the used of principle of safe-by-design concept could be a proper solution.
Who should attend: This short course is appropriate for anyone, from academia, industry, research, suppliers of devices and products based on nanomaterials, with an awareness in nanomaterial risks. In special, those involved in the creation and consumption of nanomaterials including material designers and companies. The lectures would also be of benefit to researchers working with nanomaterials as well as to decision makers, peoples working in risk assessment and policy support.
Course Outline:

1. Introduction in the field of polymeric nanobiomaterials for medical applications.

2. Types of nanomaterials and major methods for their synthesis

3. Some comments related with biocompatibility and functionalization of bionanomaterials

4. Targeted drug delivery devices based on nanomaterials

5. Some comments related with nanotoxicology and remediation

Certification: Attendees will be awarded a certificate of attendance
Note: This is an open (public) course and may be subject to minimum numbers attending

 

 

Implementation of Safe-by-Design approach for polymeric nanobiomaterials used for drug delivery. Case study: Chitosan
Location: Advanced Environmental Research Laboratories, Timisoara (Romania)
Duration: 21 February 2019 (12:00 – 20:00)
Main speakers: Prof. Dr. Vasile OSTAFE, Prof. Dr. Adriana ISVORAN
Overview: Nanomaterials have applications in various fields like healthcare, cosmetics, electronics, food and many other areas. Although nanomaterials have so many applications, there are evidences that they represent also potential risks for workers that produce them and sometime even for the user of the final products. It is widely recognized that there is a need for safe working practices and methods for testing the potential risk on nanoproducts upon the end-users. This awareness course is based on the current knowledge of nanomaterial hazards underlined in worldwide recognized best practice (e.g. ISO, OECD), combined with the newest results on research in the field.
Objectives: To provide applicants with an understanding of the principle of “Safe-by-Design” concept an its application to nanomaterials. The lectures will cover also information related to the possible hazards of nanomaterials and up-to-date knowledge of how these can be administered.
Who should attend: This short course is intended for student with basic knowledge about nanomaterials, toxicology and environmental protection. Nevertheless the lectures can present interest for anyone with an awareness in nanomaterial risks. The lectures would also be of benefit to researchers working with nanomaterials.
Course Outline:

1. Short introduction to nano-biotechnology

2. Potential risks of nanomaterials based-products

3. Safe-by-design principles

4. Case study: application of the safe-by-design concept to fabrication of chitosan based nanomaterials, with application in medicine and pharmacy.

Certification: Attendees will be awarded a certificate of attendance
Note: This is an open (public) course and may be subject to minimum numbers attending

 

COMPUTATIONAL METHODS TO PREDICT THE BIOLOGICAL EFFECTS OF ADDITIVES USED IN MEDICAL APPLICATIONS
Location: to be decided at face-to-face meeting in Switzerland (18 December 2017)
Duration: proposed 0.5 day
Overview: Nanomaterials have applications in electronics, healthcare, cosmetics, and other areas. The potential risks of working with and using nanomaterials have been widely recognized, as has the need for safe working practices. Every employer has duty-of-care responsibilities to assess and manage the risks presented in the workplace. This awareness course is based on the current knowledge of nanomaterial risks highlighted in internationally recognized best practice (e.g. ISO, OECD), combined with approaches that are used by leading nanomaterial research institutions.
Objectives: To provide participants with an understanding of the potential risks of nanomaterials and current knowledge of how these can be managed
Who should attend: This short course is suitable for anyone with an interest in nanomaterial risks and what to do about them. In particular, those involved in the manufacture and use of nanomaterials including material developers and manufacturers as well as people from companies who use nanomaterial-enabled products such as sprays and coatings.

The course would also be of interest to researchers working with nanomaterials as well as Safety and Health Professionals who need to carry out risk assessments and provide EHS support. Others who provide policy support will also find this informative. 

Course Outline:

1. Introduction to nanomaterials
2. Potential risks of nanomaterials
3. Current approaches to managing the risks of nanomaterials

Certification: Attendees will be awarded a certificate of attendance
Note: This is an open (public) course and may be subject to minimum numbers attending

 

NANOMATERIALS BASED-PRODUCTS AWARENESS
Location: to be decided at face-to-face meeting in Switzerland (18 December 2017)
Duration: proposed 0.5 day
OverviewNanomaterials have applications in various fields like healthcare, cosmetics, electronics, food and many other areas. Although nanomaterials have so many applications, there are evidences that they represent also potential risks for workers that produce them and sometime even for the user of the final products. It is widely recognized that there is a need for safe working practices and methods for testing the potential risk on nanoproducts upon the end-users. This awareness course is based on the current knowledge of nanomaterial hazards underlined in worldwide recognized best practice (e.g. ISO, OECD), combined with the newest results on research in the field.
Objectives: To provide applicants with an understanding of the possible hazards of nanomaterials and up-to-date knowledge of how these can be administered.
Who should attend: This short course is appropriate for anyone with an awareness in nanomaterial risks and what to do about them. In special, those involved in the creation and consumption of nanomaterials including material designers and companies as well as people from companies who use nanomaterial-enabled products such as sprays and coatings. The lectures would also be of benefit to researchers working with nanomaterials as well as to decision makers, peoples working in risk assessment and policy support.
Course Outline:
1. Introduction to nanomaterials based-products
2. Potential risks of nanomaterials based-products
3. Current approaches to managing the risks of nanomaterials based-products
Certification: Attendees will be awarded a certificate of attendance
Note: This is an open (public) course and may be subject to minimum numbers attending

 

NANOMATERIALS AND NANOSTRUCTURES: SYNTHESIS AND CHARACTERIZATION
Educational level Second cycle (master)

Third cycle (PhD students)

Last day of application: March 15, 2019
Duration: Module: 7 days with 2 h lectures, 4 h laboratory works per day
Examination: Take-home assignment, presentation
Objectives: To provide students with an overview of nanomaterials and nanostructures, the fundamental principles guiding the unique properties of nanomaterials, the synthesis as well as techniques for the characterization of nanomaterials and nanostructures
Who should attend: Postgraduate students.

Students should have taken all basic chemistry courses including organic chemistry, physical chemistry, inorganic chemistry, biochemistry and analytical chemistry.

Course Outline: The course is arranged as a lecture series comprising of a number of individual lectures. These lectures are centered around the course textbook plus additional materials selected from literature. The following topics will be covered:

Introduction to nanomaterials and nanostructures

Methods of characterization

Fabrication of nanostructures

Nanosurface and surface energy

Molecular self-assembly

Carbon-based nanomaterials

Synthesis of nanomaterials

Course materials: All course materials will be based on lectures that will be available to the enrolled students via the e-learning platform
Certification: 7 ECTS will be awarded to the students that will pass the examination

Attendees will be awarded a certificate of attendance

Note: This is an open (public) course and may be subject to minimum numbers attending – recommended group size 20-25 students

 

COLLOIDAL PHENOMENA IN NATURAL SYSTEMS
Educational level Second cycle (master)

Third cycle (PhD students)

Last day of application: March 15, 2019
Duration: Module: 7 days with 2 h lectures, 4 h laboratory works per day
Examination: Take-home assignment, presentation
Objectives: To provide students with an overview of nanomaterials and nanostructures, the fundamental principles guiding the unique properties of nanomaterials, the synthesis as well as techniques for the characterization of nanomaterials and nanostructures
Who should attend: Postgraduate students.

Students should have taken all basic chemistry courses including organic chemistry, physical chemistry, inorganic chemistry, biochemistry and analytical chemistry.

Course Outline:
  • Clay Suspensions and Colloidal Systems in General
  • Properties of Hydrophobic Sols
  • The Theory of the stability of Hydrophobic Sols
  •  Successes of the Theory of Stability- Further Theories and Refinements
  •  Clay Mineralogy
  • Particle Size And Shape, Surface area. And Density of Charge
  • Electric Double-Layer Structure and Stability of Clay Suspensions
  • Peptization of Clay Suspensions
  • Technological Applications of Stability Control: Sedimentation, Filtration and Flow Behaviour
  • Interlamellar and Osmotic Swelling- Applications
  • Electrokinetic and Electrochemical Properties of Clay- Water Systems
  • Sedimentation and Diffusion and their Equilibrium
  • Solution thermodynamics: Osmotic and Donnan Equilibrium
  • The Viscosity of Dilute Suspensions
  •  Van der Waals Attraction and Flocculation
  • The electric Double Layer
  • Electrophoresis and other Electrokinetic Phenomena
  • Electrostatic Interactions in Colloidal Systems
  • Forces in Colloidal Systems
  • Colloidal Stability
  • Colloidal Sols
  • Pair interaction
  • Rheology
Course materials: All course materials will be based on lectures that will be available to the enrolled students via the e-learning platform
Certification: 7 ECTS will be awarded to the students that will pass the examination

Attendees will be awarded a certificate of attendance

Note: This is an open (public) course and may be subject to minimum numbers attending – recommended group size 20-25 students
ECOLOGICAL CHEMISTRY
Educational level Second cycle (master)

Third cycle (PhD students)

Last day of application: March 15, 2019
Duration: Module: 7 days with 2 h lectures, 4 h laboratory works per day
Examination: Take-home assignment, presentation

Student should after the course understand and be able to discuss basic principles of chromatography and detectors used. The student should be able to choose the optimal separation parameters and predict the separation for a given problem.

 

Objectives: The student should understand the basic principles of chromatography and be able to handle the chromatography equipment eg. medium pressure liquid chromatography, and high pressure liquid chromatography, using detectors as MS and UV
Who should attend: Postgraduate students.

Students should have taken all basic chemistry courses including organic chemistry, physical chemistry, inorganic chemistry, biochemistry and analytical chemistry.

Course Outline: Lectures, and lab-orations, sample preparations and clean up, from biological matrixes. Separation problems will be taken from terrestrial and aquatic, toxicology, biochemistry, molecular biology.

Oral environment presentations of given topics and discussions of actual environmental problems.

 

Course materials: All course materials will be based on lectures that will be available to the enrolled students via the e-learning platform
Certification: 7 ECTS will be awarded to the students that will pass the examination

Attendees will be awarded a certificate of attendance

Note: This is an open (public) course and may be subject to minimum numbers attending – recommended group size 20-25 students